Just learned about the Kaprun disaster in which 155 people lost their lives when an underground train caught fire.
There were only 12 survivors all of whom followed the advice of a retired firefighter who advised them to run downhill through the flames in the rear of the train.
The steep incline of the tunnel acted as a blast furnace that sucked in fresh air from the low end and funneled toxic smoke to the high end.
Not sure how applicable this will be to anyone here, but I thought it a great example of how a little more widespread knowledge of how fire works could have saved a lot of lives.
Tl;dr fire bad but smoke worse. Get to fresh air.
I guess if you ever find yourself owning the high ground to fire this is useful, or find yourself in a tube whose bottom is aflame.
Might also be that your only way out of a room is through a burning doorway. Gotta find a bottle of water and Riddick that shit.