As a heterosexual male, “best boy” is a topic I am unlikely to bring up of my own accord, but I would have no difficulty or discomfort engaging on the topic with ladies and/or gaybros.

That said, sometimes a male character is so compelling he gets ironically assigned the title “best girl”.

Big brassy 1950s style jazz. Love it.

I don’t believe I’ve seen much discussion of the ED for Tonari no Seki Kun (https://youtu.be/oIKB7i6fcmk), and it is amazing.