Undiagnosed (aside from TTT at home) EDS/POTS here (mild), I biked enough to notice a difference but I didn’t hit the point where it aligned with this post (maybe because I don’t really sweat, stress on my body changes the effect?). Even with inactivity, muscle loss is not an issue for me.
Though the biggest issue with cycling for me is that I don’t really have (m)any destinations, distance makes most trips not viable for what they are (particularly factoring in return trip) or add complication when it comes to hours or weather. Daylight savings ending combined with shorter days ruined it for me, too.
Yes, spring of 2444 with my brain in a jar.